Exemestane / Aromasin Cancer Kurapa Anti Estrogen Steroids Yekucheka / Kuunganidza Cycle
Quick Detail
Exemestane
Alias: Aromasin;Exemestan
Kuonekwa: Ichena kana Inenge Yakachena Crystalline Powder
Product content: ≥ 99%CAS:107868-30-4
Molecular formula: C20H24O2
Masikuru Kurema: 296.40
Shandisa: inoshandiswa mukurapa kenza yemazamu yemazamu.uye inoshandiswa seyamuro mukurapa kenza yemazamu yekutanga.
Iwe unogona zvakare kuinzwa ichinzi Aromasin, rinova iro rinonyanya kuzivikanwa zita rechiratidzo.Kune akati wandei mamwe mabhureki eexemestane, ese ane muyero wakafanana wemushonga.
Dosage Tips
Usual Adult Dose yeGomarara rezamu:
25 mg muromo kamwe pazuva
Comment:
- Mushonga uyu unofanirwa kupiwa mushure mekudya.
Zvishandiso:
- Adjuvant kurapwa kwevakadzi vane postmenopausal vane estrogen-receptor yakanaka kenza yemazamu yekutanga vakawana makore maviri kusvika matatu etamoxifen uye vanochinjirwa kuexemestane kuti vapedze makore mashanu akateedzana eadjuvant hormonal therapy.
- Kurapwa kwegomarara rezamu repamusoro muvakadzi vepomenopausal vane chirwere chakawedzera zvichitevera tamoxifen kurapwa.
Tsanangudzo
Aromasin (Exemestane acetate) ndeimwe yeaya asinganzwisisike makomisheni ayo hapana anonyatsoziva zvekuita nawo.Icho chizvarwa chechitatu Aromatase Inhibitor (AI) seArimidex (Anastrozole) uye Femera (Letrozole).
chizvarwa chechitatu aromatase inhibitors, inoshandiswa mukurapa kenza yemazamu yemazamu uye inoshandiswa seyamuro mukurapa kenza yezamu yekutanga.
● Aromasin ndechimwe chemakemikari ane simba zvikuru ekudzvinyirira eestrogen.
● Aromasin ndechimwe chezvakanakisa zvinosanganisa kudzikisa kunhuhwirira kunoita masteroid.
● Aromasin inowanikwa kune vanovaka muviri vanotora anabolic steroids.
● Aromasin inozivikanwawo seExemestane.
● Inoshanda nekuvhara enzyme aromatase, zvichizovhara kugadzirwa kweestrogen.
● Aromasin zvakare imhando ye.antineoplastic (hormonal) raw materials.
Aromasin inoshandiswa kurwisa gomarara rezamu uye kusimudza testosterone mumuviri.
Exemestane inovhara maitiro ekunhuhwirira.Saka inoderedza huwandu hweesrogen mumuviri.Mukutanga kenza yemazamu, kutora exemestane kunogona kubatsira kumisa gomarara rezamu kudzoka.Mugomarara rezamu repamusoro masero egomarara anogona kukura zvishoma nezvishoma kana kurega kukura zvachose.
Exemestane inonzi aromatase inhibitor.Izvi zvinoreva kuti inovhara enzyme aromatase (inowanikwa mumhasuru yemuviri, ganda, zamu nemafuta), iyo inoshandiswa kushandura androgens (mahomoni anogadzirwa neadrenal glands) kuita estrogen.Mukushaikwa kweesrogen, mapundu anoenderana nehomoni iyi pakukura anoderera
Zvakanakira Exemestane
>>.Kuvaka muviri
Steroidal Exemestane inhibitor iyo inoshanda nekudzikisa huwandu hweesrogen inogadzirwa nemuviri.Inoshanda nekugadzirisa kutendeuka kweTesttosterone muesrogen uye muvhareji weyero yeesrogen kudzvinyirira ndeye 85%.Mushonga wacho unoderedzawo mazinga e-estradiol anosvika makumi mashanu muzana, pamwe chete nekuwedzera zvakanyanya mazinga e testosterone.
Exemestane inhibitor inoshanda nekudzivisa synthesis yeestrogen.Inoshanda pakuwedzera Testosterone uye IGF mazinga mumuviri.Mushonga wacho unobatsirawo zvikuru panguva ye post cycle therapy regime apo munhu ari kuedza kudzorera mazinga e Testosterone echisikigo kuti adzivise kuparara kwemashure.
>>.Anti-estrogen mushonga
Kuzivikanwa seimwe yemishonga inodhura zvakanyanya, Exemestane ndeimwe yeakachengeteka anti-estrogen zvinodhaka izvo zvinonyanya kushandiswa nevatambi uye bodybuilders.Mukurapa mushonga wacho unonyanya kunyorerwa kurapwa kenza yemazamu.Inowanzo kunzi Selective Estrogen Receptor Modulator (SERM), yakamboshandiswa kudzivirira gynocomastia.
Kushanda kweExemestane
A)Exemestane yekudzivirira kenza yemazamu:
Chemoprevention yegomarara rezamu inzira inoshanda yekudzikisa kuitika kwechirwere ichi muvakadzi vari panjodzi.Vamiririri vekutanga kuratidza zvakakosha chemopreventive effect vaiva SERMs tamoxifen uye raloxifen.
Ongororo yakagadziridzwa yakazara yeese bvunzo yekudzivirira yeSERM yakaratidza kuti vanokwanisa kudzikisa chiitiko chegomarara rezamu muvakadzi vane njodzi huru uye yepakati, mhedzisiro inotsigirwa nekuderedzwa kweER-positive invasive cancer cancer.
B)Exemestane chizvarwa chechitatu chisingachinjiki steroidal inactivator yearomatase enzyme uye inoshanda mune zvese zvirongwa zvekurapa kenza yemazamu, kusanganisira chemoprevention.
Mune metastatic setting, exemestane yakaongororwa zvakanyanya seyekutanga-mutsara, yechipiri-mutsara, uye mberi-mutsara kurapwa uye ikozvino yakanyoreswa kurapwa kwevakadzi vepamenopausal vane advanced hormone-receptor-positive kenza yemazamu vane chirwere chakawedzera zvichitevera antiestrogen. kurapwa.
Zvecherechedzo, iko kushomeka kwemuchinjiko-kupokana neNSAIs kunopa mimwe mikana mukutevedzana kwekurapa kweendocrine agents.Uyezve, zvichibva pamhedzisiro yekiriniki ine chinangwa, exemestane neeverolimus inomiririra nzira yekurapa inoshanda yechirwere chakafambira mberi mushure mekusangana neNSAIs.
Exemestane inowanzotenderwa zvakanaka, ine mhedzisiro yakafanana neyemamwe maAI uye inosanganisira menopausal zviratidzo, arthralgia, kurasikirwa kwemapfupa, uye kuchinjwa lipid metabolism.
